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Senior Principal Scientist, Discovery-Immunology

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This job posting is anticipated to close on Jun 22 2026. We may however extend this time period, in which case the posting will remain available on www.careers.jnj.com to accept additional applications.

Description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Biological Research

Job Category:

Scientific/Technology

All Job Posting Locations:

Cambridge, Massachusetts, United States of America

Job Description:

About Innovative Medicine

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow and profoundly impact health for humanity. Learn more at https://www.jnj.com/.

About Immunology

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Our Immunology team leads in the development of transformational medicines for immunological disorders and illnesses. You can influence where medicine is going by restoring health to millions of people living with immune diseases. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

We are searching for the best talent for a Senior Principal Scientist, Discovery Immunology to join our team in Cambridge, MA.

This role is for an experienced immunologist with a demonstrated ability to lead cross-functional discovery programs, navigate ambiguity, and develop high-performing teams.

The successful candidate will shape and advance research across multiple programs, translating complex biology into therapeutic hypotheses while operating effectively in a fast-paced, matrixed environment. In this role, they will also mentor and guide a team of scientists, contributing to a collaborative and high-performing environment.

The successful candidate will:

  • Lead discovery-stage research programs, driving strategy and execution across immunology therapeutic areas
  • Translate emerging biology into adaptable discovery strategies and develop innovative hypotheses for target validation and therapeutic concept development
  • Integrate in silico, in vitro, and in vivo data to inform decisions and advance assets, adapting approaches as new data emerge
  • Navigate shifting scientific priorities with high agility, rapidly evolving strategies and experimental direction
  • Contribute to portfolio strategy and represent programs in governance discussions
  • Operate effectively in a highly matrixed environment, partnering across functions to drive alignment and execution across programs while influencing decisions through scientific expertise and clear communication
  • Mentor and develop scientists while fostering a collaborative, accountable, and high-performing team environment
  • Lead by example and without formal authority to promote scientific rigor, effective ways of working, and drive team outcomes

Qualifications

  • Ph.D. in Immunology, Biology, or related discipline with 5-7 years of extensive drug discovery experience is required.
  • Demonstrated track record of advancing programs, leading cross-functional teams, and applying immunology expertise to inform discovery strategy is required.
  • Proven ability to operate effectively in dynamic, matrixed environments is required.
  • Strong written and verbal communication, stakeholder influence skills to drive both scientific outcomes and team development is required.
  • Experience conducting due diligence and evaluation of business development opportunities is preferred.
  • Up to 10% travel is required.

Why Join Us

You will be part of a leading Discovery Immunology organization working at the forefront of novel therapeutic discovery in immune-mediated diseases, with the opportunity to shape both scientific direction and team capability.

Subject to the terms of their respective plans, employees and/or eligible dependents are eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.

Subject to the terms of their respective plans, employees are eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).

This position is eligible to participate in the Company’s long-term incentive program.

Subject to the terms of their respective policies and date of hire, Employees are eligible for the following time off benefits:

  • Vacation –120 hours per calendar year
  • Sick time - 40 hours per calendar year; for employees who reside in the State of Washington –56 hours per calendar year
  • Holiday pay, including Floating Holidays –13 days per calendar year
  • Work, Personal and Family Time - up to 40 hours per calendar year
  • Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child
  • Condolence Leave – 30 days for an immediate family member: 5 days for an extended family member
  • Caregiver Leave – 10 days
  • Volunteer Leave – 4 days
  • Military Spouse Time-Off – 80 hours

Additional information can be found through the link below.

https://www.careers.jnj.com/employee-benefits

The anticipated base pay range for this position is: $137,000 - $235,750

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers . Internal employees contact AskGS to be directed to your accommodation resource.

#LI-Hybrid

Required Skills:

Preferred Skills:

Big Data Management, Data Reporting, Data Savvy, Drug Discovery Development, Molecular Diagnostics, Pharmaceutical Microbiology, Problem Solving, Product Development, Product Knowledge, Project Reporting, Research Proposals, Scientific Research, Standard Operating Procedure (SOP), Strategic Thinking, Sustainability, Tactical Planning, Technical Credibility

The anticipated base pay range for this position is :

$137,000.00 - $235,750.00

Additional Description for Pay Transparency:

Senior Principal Scientist, Discovery-Immunology

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